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 CASE REPORT
Year : 2005  |  Volume : 42  |  Issue : 1  |  Page : 57-59

Generalized neutrophilic dermatosis: A rare presentation of myelodysplastic syndrome


1 National Institute of Tuberculosis and Lung Diseases, Oncology Department. Baghi Hospital, Iran
2 National Institute of Tuberculosis and Lung Diseases, Oncology Department, Iran Medical School, Iran

Correspondence Address:
Nima Aghili
National Institute of Tuberculosis and Lung Diseases, Oncology Department, Iran Medical School
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.15102

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We present a 30-year-old man admitted with generalized cutaneous lesions, fever and cough. Examination of skin biopsies of a papular lesion revealed dense neutrophilic infiltration of the upper dermis, so these lesions were diagnosed as neutrophilic dermatosis. Peripheral blood examination and bone marrow findings confirmed the diagnosis of myelodysplastic syndrome with excess blasts. The cutaneous lesions improved after administration of corticosteroid and follow-up bone marrow examination revealed a normocellular marrow. One year later he referred with acute myelogenous leukemia (AML-M0). Unfortunately, he did not respond to treatment and died a few months later due to disease progression.






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