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Year : 2008  |  Volume : 45  |  Issue : 4  |  Page : 137-141

Integrated positron emission tomography/computed tomography fusion imaging: An emerging gold standard in lung cancer


1 Department of Oncology and Radiotherapy, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia
2 Department of Pathology, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia
3 Department of Nuclear Medicine, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia
4 Department of Palliative Care, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia

Correspondence Address:
S C Joshi
Department of Oncology and Radiotherapy, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang
Malaysia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.44660

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Positron emission tomography (PET) has emerged as an important diagnostic tool in the management of lung cancers. Although PET is sensitive in detection of lung cancer, but FDG (2-deoxy-2- 18 fluro-D-glucose) is not tumor specific and may accumulate in a variety of nonmalignant conditions occasionally giving false positive result. Addition of CT to PET improves specificity foremost, but also sensitivity in tumor imaging. Thus, PET/CT fusion images are a more accurate test than either of its individual components and are probably also better than side-by-side viewing of images from both modalities. PET/CT fusion images are useful in differentiating between malignant and benign disease, fibrosis and recurrence, staging and in changing patient management to more appropriate therapy. With analysis and discussion it appears that PET/ CT fusion images have the potential to dramatically improve our ability to manage the patients with lung cancer and is contributing to our understanding of cancer cell biology and in development of new therapies.






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