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 SYMPOSIUM
Year : 2011  |  Volume : 48  |  Issue : 1  |  Page : 11-17

Brain tumor and Gliadel wafer treatment


1 Department of Neurosurgery, Krishna Institute of Medical Sciences, Secunderabad, India
2 Department of Medical Oncology, Indraprastha Apollo Hospital, New Delhi, India
3 Indian Co-operative Oncology Network, Mumbai, India

Correspondence Address:
P M Parikh
Indian Co-operative Oncology Network, Mumbai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.76623

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Glioblastoma is a rapidly progressive and extremely fatal form of brain tumor with poor prognosis. It is the most common type of primary brain tumor. Even with the most aggressive conventional treatment that comprises surgery followed by radiotherapy and chemotherapy, most patients die within a year of diagnosis. Developments in molecular and cell biology have led to better understanding of tumor development, leading to novel treatment strategies including biological therapy and immunotherapy to combat the deadly disease. Targeted drug delivery strategies to circumvent the blood-brain barrier have shown efficiency in clinical trials. Gliadel wafer is a new approach to the treatment of glioblastoma, which involves controlled release delivery of carmustine from biodegradable polymer wafers. It has shown promising results and provides a silver lining for glioblastoma patients.






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