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  Table of Contents  
LETTER TO THE EDITOR
Year : 2014  |  Volume : 51  |  Issue : 4  |  Page : 474-475
 

Clinico-radiological profile with suspicion of lung cancer and its correlation with flexible TBNA (transbronchial needle aspiration) and cytological analysis-initial results from a tertiary rural setup of Ambala District, Haryana


1 Department of Respiratory Medicine, MMIMSR, Mullana, Ambala, Haryana, India
2 Department of PSM, MMIMSR, Mullana, Ambala, Haryana, India

Date of Web Publication1-Feb-2016

Correspondence Address:
Dr. S Singhal
Department of Respiratory Medicine, MMIMSR, Mullana, Ambala, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.175294

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How to cite this article:
Tangri N, Singhal S, Mehta D, Bansal S, Maini V K, Misra P, Wadhwa S, Singla S. Clinico-radiological profile with suspicion of lung cancer and its correlation with flexible TBNA (transbronchial needle aspiration) and cytological analysis-initial results from a tertiary rural setup of Ambala District, Haryana. Indian J Cancer 2014;51:474-5

How to cite this URL:
Tangri N, Singhal S, Mehta D, Bansal S, Maini V K, Misra P, Wadhwa S, Singla S. Clinico-radiological profile with suspicion of lung cancer and its correlation with flexible TBNA (transbronchial needle aspiration) and cytological analysis-initial results from a tertiary rural setup of Ambala District, Haryana. Indian J Cancer [serial online] 2014 [cited 2019 Dec 13];51:474-5. Available from: http://www.indianjcancer.com/text.asp?2014/51/4/474/175294


Sir,

Lung cancer is one of the most common malignant neoplasms globally, accounting for more cancer deaths than any other cancer. It is increasingly being recognized as the most common malignancy in males in many hospitals of India. In addition to smoking, occupational exposure to carcinogens, indoor air pollution and dietary factors have recently been implicated in the causation of lung cancer. Squamous cell carcinoma is still the most common histological type in India in contrast to the Western countries, although adenocarcinoma is becoming more common.[1] Lung cancers are common after 50 years of age, which poses a challenge for pulmonologist to diagnose. Sputum cytology and non-invasive diagnostic methods are quite insufficient in accurate diagnosis. In such cases, transbronchial needle aspiration (TBNA) with flexible bronchoscopy proves to be a useful tool for diagnosing lung cancer accurately.[2],[3] Our aim and objectives was to study the clinico-radiological profile of suspected cases of lung cancer and its correlation with fiber-optic TBNA and cytological analysis. Forty patients with suspicion of lung cancer attending chest out-patient department from June, 2011 to November, 2011 were evaluated with chest X-ray and contrast enhanced computed tomography. Suspected cases were further evaluated with flexible bronchoscopy and TBNA and cytopathological analysis. Flexible bronchoscopy helped in confirmatory diagnosis of 75% cases of carcinoma lung, out of which most of the cases were that of adenocarcinoma (54%), followed by squamous cell carcinoma (16%). In 25% cases, it was in favor of inflammatory pathology. Males (80%) were more susceptible to develop lung cancer in comparison with females (20%) and 63% of total cases were in the age group of 51-70 years. Complete clinical examination of suspected lung cancer patients revealed that most common sign associated with development of lung cancer was clubbing (48%), followed by pleural effusion (15%), facial puffiness (13%), lymphadenopathy (13%), lung collapse (13%), bony tenderness (8%), superior vena caval obstruction (5%) and change in voice (4%). Radiological findings suggested higher prevalence of tumor mass shadows (60%), with lung collapse seen in 38% of cases followed by metastases (30%), hilar prominence (25%), diaphragm paralysis (20%), pleural effusion, loculated cavity and rib erosion in 13% of the cases. Most reliable bronchoscopic signs of carcinoma lung were widened carina and bronchial lumen narrowing (25%) followed by endobronchial growth (20%), mucosal hyperemia bleed on touch (13%) and vocal cord paralysis (10%). Flexible bronchoscopy was found to be a safe, better and more efficient procedure for diagnosis of patient with suspicion of lung cancer.

 
  References Top

1.
Behera D, Balamugesh T. Lung cancer in India. Indian J Chest Dis Allied Sci 2004;46:269-81.  Back to cited text no. 1
    
2.
Ernst A, Silvestri GA, Johnstone D, American College of Chest Physicians. Interventional pulmonary procedures: Guidelines from the American college of chest physicians. Chest 2003;123:1693-717.  Back to cited text no. 2
    
3.
Wang KP, Marsh BR, Summer WR, Terry PB, Erozan YS, Baker RR. Transbronchial needle aspiration for diagnosis of lung cancer. Chest 1981;80:48-50.  Back to cited text no. 3
    




 

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