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Year : 2014  |  Volume : 51  |  Issue : 7  |  Page : 67-71

S100 protein in breast tumor


1 Department of Radiology, and Geriatrics, Tianjin Geriatric Institute, Tianjin Medical University General Hospital, Tianjin, China
2 Department of Internal Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300052, China

Correspondence Address:
W Zhang
Department of Radiology, and Geriatrics, Tianjin Geriatric Institute, Tianjin Medical University General Hospital, Tianjin
China
X Men
Department of Internal Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300052
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.154046

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S100 protein is the largest subtribe in calcium binding protein family. According to recent researches, abnormal expression of S100 protein is often related to tumor, including breast tumor. Breast tumor is the most common malignant disease in female with high mortality mainly due to metastasis. Estimating early diagnostic and prognostic markers are helpful to conduct treatment for patients with breast cancer. Accumulating investigations focused on the role of S100 proteins in breast tumor development and metastasis. This paper summarizes the expression situation of S100 proteins in breast tumor as well as its effects on metastasis and prognosis of breast tumor.






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