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 REVIEW ARTICLE
Year : 2015  |  Volume : 52  |  Issue : 3  |  Page : 413-416

Neoadjuvant chemotherapy and surgery versus surgery alone in resectable esophageal cancer


Department of Surgical Oncology, Asian Institute of Oncology, Mumbai, Maharashtra, India

Correspondence Address:
K Bushan
Department of Surgical Oncology, Asian Institute of Oncology, Mumbai, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.176743

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The aim of this article is to review randomized and non-randomized trials and meta-analysis comparing neoadjuvant chemotherapy (NAC) plus surgery versus surgery alone in resectable esophageal cancers. The article examines the value of NAC as a standard of care in the era of multimodality treatment with availability of different therapeutic options. The emphasis is on assessment of benefit of NAC in terms of survival (long and short term) rate of RO resection in resectable esophageal cancers of any histopathologic type. The in-hospital post-operative morbidity and mortality in NAC group, chemotherapeutic drug regimens and their response rates and optimal number of cycles to be used will also be addressed






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