Indian Journal of Cancer
Home  ICS  Feedback Subscribe Top cited articles Login 
Users Online :33
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded417    
    Comments [Add]    
    Cited by others 3    

Recommend this journal


Year : 2015  |  Volume : 52  |  Issue : 4  |  Page : 580-585

Quality of life measures in glioma patients with different grades: A preliminary study

1 Department of Neuropsychiatric, MBI-Lab, China Medical University Hospital, Taichung, Taiwan; Department of Biochemistry, University of Madras, Guindy Campus, Chennai, Tamil Nadu, India
2 Department of Biochemistry, University of Madras, Guindy Campus, Chennai, Tamil Nadu, India

Correspondence Address:
A J Vanisree
Department of Biochemistry, University of Madras, Guindy Campus, Chennai, Tamil Nadu
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-509X.178395

Rights and Permissions

BACKGROUND: Plethora of information exists in the literature on pathology of the glioma while prevailing research data on quality-of-life (QOL) of glioma patients marks dearth thus demanding more studies. AIMS: In this study, we examined the QOL of different grades of glioma patients among the Chennai population in India. MATERIALS AND METHODS: A total of 162 patients with different grades of glioma enrolled from August 2007 to February 2011, at their first contact to Department of Neurology and Neurosurgery, Government General Hospital, Chennai, India were included and their QOL was assessed by European Organization for Research and Treatment of Cancer Core QOL questionnaire (EORTC QLQc-30), EORTC brain cancer module (QLQ BN-20). RESULTS AND CONCLUSION: Both low and high grade glioma (LGG and HGG) patients had poor mean scores in social functioning (87.0), physical functioning (82.0) and emotional functioning (75.2) and role functioning (58.9). The mean scores on cognitive functioning (61.9) and global QOL (60.3) were better. Age, Karnofsky performance status, World Health Organization grades showed significant associations with all functional scales. The percentage values were higher for symptoms of fatigue (76.9%), pain (71.5%), financial difficulties (77.6%) and appetite loss (38.46%) in both LGG and HGG. Similarly, with respect to QLQ-BN20 domains, HGG patients showed more symptoms than low grade with a significant correlation in communication deficit problems (P = 0.02), headache (P = 0.04), seizures (P < 0.01), hair loss (P < 0.05) than the other symptoms. This initial assessment suggests that an increasing burden of symptoms exists, with poor QOL and survival, which has become a major concern in different grades of glioma patients.


Print this article     Email this article

  Site Map | What's new | Copyright and Disclaimer
  Online since 1st April '07
  © 2007 - Indian Journal of Cancer | Published by Wolters Kluwer - Medknow