|LETTER TO THE EDITOR
|Year : 2016 | Volume
| Issue : 2 | Page : 225
In silico analysis to predict lack of carcinogenicity of Zika virus
B Joob1, V Wiwanitkit2
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Tropical Medicine, Hainan Medical University, Haikou, China
|Date of Web Publication||6-Jan-2017|
Sanitation 1 Medical Academic Center, Bangkok
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Joob B, Wiwanitkit V. In silico analysis to predict lack of carcinogenicity of Zika virus. Indian J Cancer 2016;53:225
Zika virus is an emerging viral pathogen that causes the problem worldwide at present. The Zika virus infection can cause acute febrile hemorrhagic fever, and it can also induce fetal abnormality and congenital defect., The great concern on this new emerging disease is its effect on the cell that causes abnormal embryogenesis. In oncology, another important concern is on the carcinogenicity property of the Zika virus infection. In fact, many viruses, such as hepatitis viruses, are proved to cause cancer in long-term. Here, the authors use standard in silico analysis for prediction of carcinogenicity of the Zika virus. The standard tool, Way2Drug, which is based on Prediction of Activity Spectra for Substances Technology. Based on study on both cancer cell line and nontumor cell line condition, no carcinogenicity of the Zika virus can be seen. Based on this in silico study, it can imply that Zika virus should induce no malignancy. Further long-term study and observation on this topic are recommended.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
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