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 ORIGINAL ARTICLE
Year : 2016  |  Volume : 53  |  Issue : 2  |  Page : 284-287

An audit of cytoreductive surgeries in ovarian cancer from a rural based cancer center


1 Department of Surgical Oncology, Malabar Cancer Centre, Thalassery, Kerala, India
2 Department of Clinical Hematology and Medical Oncology, Malabar Cancer Centre, Thalassery, Kerala, India
3 Department of Radiation Oncology, Malabar Cancer Centre, Thalassery, Kerala, India
4 Department of Imageology, Malabar Cancer Centre, Thalassery, Kerala, India
5 Department of Cancer Registry, Division of Clinical Research and Biostatistics, Malabar Cancer Centre, Thalassery, Kerala, India
6 Department of Clinical Laboratory Services and Translational Research, Division of Oncopathology, Malabar Cancer Centre, Thalassery, Kerala, India

Correspondence Address:
S B Dessai
Department of Surgical Oncology, Malabar Cancer Centre, Thalassery, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.197743

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Background and Objective: Ovarian cancers are frequently seen at an advanced stage in our center. This audit was planned to see the morbidity and efficacy of different types of cytoreductive surgeries (radical vs. ultra-radical) done in such patients. Methods: This was a retrospective analysis of all ovarian cancer patients who underwent cytoreductive surgery at our center from January 2009 to August 2013. The case records of these patients were reviewed and the demographic, disease-related and treatment-related data were extracted. Results: Fifty-fivepatients were identified. Ten (18.2%) patients underwent primary cytoreduction while 45 patients had (81.8%) interval cytoreduction. The resections achieved were optimal in 50 patients (90.9%) and suboptimal in five patients (9.1%). The postoperative median blood loss was 400 (350–600) mL. The median time interval for surgery was 4.0 h (3–5 h). The type of resection achieved (optimal vs. suboptimal) was the only factor affecting the progression free survival (PFS) (Hazard ratio = 0.08 95% confidence interval 0.02–0.3). There was no significant difference in postoperative morbidity in patients undergoing the ultra-radical surgery as compared to those who underwent radical surgery. Conclusion: Optimal cytoreduction may improve PFS in advanced ovarian cancer patients and needs to be done even if it mandates an ultra-radical surgery.






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