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 CASE REPORT
Year : 2020  |  Volume : 57  |  Issue : 2  |  Page : 209-211

Unusual cause of seizure in a child: Intracranial calcified metastasis of osteosarcoma


1 Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
2 Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Venkatesh Hosur Ananthashayana
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijc.IJC_796_18

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Intracranial parenchymal calcification has both benign and malignant etiologies. Calcifications by malignant etiologies are comparatively rare. Malignant calcification has numerous causes. Calcified brain metastasis from osteosarcoma is one such cause. We present histopathologically confirmed intracranial calcified metastasis in a 10 year old girl. This girl had received treatment for primary osteosarcoma of the left femur with pulmonary metastases. Radiological imaging with Positron emission tomography–computed tomography revealed an intracranial calcified lesion in the frontal lobe and she was successfully operated for the same. The malignant causes of intracranial calcifications are reviewed and radiological differential diagnoses of malignant intracranial calcifications are discussed in this case report. Prior history, strong clinical suspicion, and radiological imaging are needed to arrive at the diagnosis of intracranial calcified metastasis from primary osteosarcoma of the appendicular skeleton.






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