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Year : 2006  |  Volume : 43  |  Issue : 1  |  Page : 26--29

Squamous cell carcinoma of the maxillary sinus: A Tata Memorial Hospital experience

Sajid S Qureshi1, Devendra A Chaukar1, Sanjay D Talole2, Anil K Dcruz1 
1 Department of Head and Neck Services, Tata Memorial Hospital, Parel,Mumbai - 400012, India
2 Department of Biostatistics, Tata Memorial Hospital, Parel, Mumbai - 400012, India

Correspondence Address:
Sajid S Qureshi
Department of Head and Neck Services, Tata Memorial Hospital, Parel,Mumbai - 400012
India

Background: The optimal treatment of maxillary sinus carcinoma remains to be defined and there is a paucity of Indian studies on the subject. Aims: To present experience of management of squamous cell carcinoma of the maxillary sinus treated with curative intent at a single institution. Settings and Design:Retrospective study of patients with squamous cell carcinoma of the maxillary sinus who presented between 1994 to 1999. materials and Methods:The records of 73 patients with squamous cell carcinoma of the maxillary sinus were analyzed. Sixty-two patients were evaluable. Forty patients (65%) were treated with surgery followed by postoperative radiotherapy, five patients (8%) were treated with radiotherapy alone, five patients (8%) were treated with surgery alone; 12 patients (19%) received chemotherapy. Statistical analysis used: Statistical analysis was done using Kaplan-Meier method. Results: The majority of patients presented with locally advanced disease (52, 84%); nodal involvement was observed in five patients (8%). The most common site of recurrence was at the primary site, which was observed in 28 patients (45%) and regional failures occurred in 10 (16%). The 3 and 5-year overall survival was 38% and 35% and the disease free survival was 29% and 26% respectively. The 5-year overall survival after surgery and postoperative radiotherapy was 42%. Conclusions:The majority of patients present with advanced disease resulting in poor outcomes to conventional treatment modalities. Locoregional tumor progression remains a significant pattern of failure. New approaches such as neoadjuvant or concomitant chemoradiotherapy with aggressive surgery need to be considered and evaluated in prospective studies.


How to cite this article:
Qureshi SS, Chaukar DA, Talole SD, Dcruz AK. Squamous cell carcinoma of the maxillary sinus: A Tata Memorial Hospital experience.Indian J Cancer 2006;43:26-29


How to cite this URL:
Qureshi SS, Chaukar DA, Talole SD, Dcruz AK. Squamous cell carcinoma of the maxillary sinus: A Tata Memorial Hospital experience. Indian J Cancer [serial online] 2006 [cited 2020 Jan 20 ];43:26-29
Available from: http://www.indianjcancer.com/article.asp?issn=0019-509X;year=2006;volume=43;issue=1;spage=26;epage=29;aulast=Qureshi;type=0