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Year : 2018  |  Volume : 55  |  Issue : 2  |  Page : 134--137

Primary cutaneous B-cell lymphoma: A single-center 5-year experience

Linu Abraham Jacob, Vikas Asati, KC Lakshmaiah, Babu K Govind, Dasappa Lokanatha, Suresh MC Babu, KN Lokesh, AH Rudresh, LK Rajeev, Nikita J Mulchandani, Abhishek Anand, Deepak Koppaka, Suma Narayana Mysore 
 Department of Medical Oncology, Kidwai Cancer Institute, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Vikas Asati
Department of Medical Oncology, Kidwai Cancer Institute, Bengaluru, Karnataka
India

BACKGROUND: Skin is the second most common site for extranodal non-Hodgkin's lymphoma (NHL). Most primary cutaneous NHLs are of T-cell origin (70%). Primary cutaneous B-cell lymphoma (PCBCL) is a rare entity. MATERIALS AND METHODS: Patients diagnosed with PCBCL between January 2012 and July 2017 at our center were retrospectively analyzed. RESULTS: Eight patients of PCBCL were diagnosed. Three patients (37.5%) were males while 5 patients (62.5%) were females. The median age at diagnosis was 45 years (range, 18–60 years). Scalp was the most common site of involvement (50% of the patients). Diffuse large B-cell lymphoma (DLBCL) was the most common histology (63%), with leg-type DLBCL diagnosed in 1 patient. Two patients had primary cutaneous follicle center lymphoma, whereas the remaining 1 patient had precursor B-lymphoblastic lymphoma. All 5 DLBCL cases were treated with CHOP chemotherapy, and rituximab was given to 3 patients. Of the primary cutaneous follicle center lymphomas, 1 patient with stage II disease was treated with CHOP and is alive without recurrence for the past 5 years, whereas the other patient is on observation alone. The patient with precursor B-lymphoblastic lymphoma was started on MCP-841 protocol; however, the patient did not complete the treatment and died after 11 months. CONCLUSIONS: PCBCL is a heterogeneous group of diseases and dividing them into subtypes, based on morphology and immunophenotype, has therapeutic implications.


How to cite this article:
Jacob LA, Asati V, Lakshmaiah K C, Govind BK, Lokanatha D, Babu SM, Lokesh K N, Rudresh A H, Rajeev L K, Mulchandani NJ, Anand A, Koppaka D, Mysore SN. Primary cutaneous B-cell lymphoma: A single-center 5-year experience.Indian J Cancer 2018;55:134-137


How to cite this URL:
Jacob LA, Asati V, Lakshmaiah K C, Govind BK, Lokanatha D, Babu SM, Lokesh K N, Rudresh A H, Rajeev L K, Mulchandani NJ, Anand A, Koppaka D, Mysore SN. Primary cutaneous B-cell lymphoma: A single-center 5-year experience. Indian J Cancer [serial online] 2018 [cited 2019 Sep 22 ];55:134-137
Available from: http://www.indianjcancer.com/article.asp?issn=0019-509X;year=2018;volume=55;issue=2;spage=134;epage=137;aulast=Jacob;type=0