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 REVIEW ARTICLE
Year : 2015  |  Volume : 52  |  Issue : 2  |  Page : 232-234

Circulating tumor cells in oral squamous cell carcinoma: An insight


Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Hospital and Research Centre, Bommanahalli, Bangalore, Karnataka, India

Correspondence Address:
B V Prakruthi
Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Hospital and Research Centre, Bommanahalli, Bangalore, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-509X.175844

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Circulating tumor cells (CTCs) are those cells present in the blood and have antigenic and/or genetic characteristics of a specific tumor type. CTCs can be detected in the peripheral blood of cancer patients. Various techniques are available for detection of CTCs, which provide evidence for future metastasis. CTCs may provide new insight into the biology of cancer and process of metastasis in oral squamous cell carcinoma (OSCC). The detection of CTCs may represent a new diagnostic tool for predicting the occurrence of metastatic disease in OSCC and endow with the treatment strategies to efficiently treat and prevent cancer metastasis. This review gives an insight into the significance of CTCs and different techniques for detection of CTCs.






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