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Year : 2017  |  Volume : 54  |  Issue : 4  |  Page : 616--620

Outcomes of surgically treated oral cancer patients at a tertiary cancer center in India

Deepa Nair1, Hitesh Singhvi1, Manish Mair1, Burhanuddin Qayyumi1, Anuja Deshmukh1, Gouri Pantvaidya1, Sudhir Nair1, Pankaj Chaturvedi1, Sarbani Ghosh Laskar2, Kumar Prabhash3, Anil DCruz4 
1 Department of Head and Neck Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India
2 Radiation Oncologist, Tata Memorial Centre, Mumbai, Maharashtra, India
3 Medical Oncologist, Tata Memorial Centre, Mumbai, Maharashtra, India
4 Director, Tata Memorial Centre, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Deepa Nair
Department of Head and Neck Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra
India

BACKGROUND: Oral cancers are one of the most common cancers in India. Surgery is the main modality of treatment for oral cancer patients. It is important to understand the postoperative morbidity and mortality as it influences patient outcomes. AIM: The aim of this study was to determine oral cancer patients' characteristics, treatment details, 30-day morbidity and mortality, and survival outcomes. SETTINGS AND DESIGN: This was a retrospective analysis of prospectively collected data in a tertiary cancer center. MATERIALS AND METHODS: This study included 850 surgically treated oral cancer cases between January and December 2012. STATISTICAL ANALYSIS: We performed univariate survival analysis by log-rank test, and all significant (P < 0.05) variables underwent multivariate analysis using Cox regression. RESULTS: The median age was 52 years and the male-to-female ratio was 3.4:1. Nearly one-third of the patients received some form of prior treatment. Buccal mucosa (BM) was the most common subsite (64.94%). BM cancers (81.1%) were more likely to present in advanced stage compared to tongue cancers (52%) (P = 0.000). The incidence of postoperative morbidity and mortality was 36.4% and 0.9%, respectively. Complications were higher in cT3-4 (P = 0.000), cN positive (P = 0.000), and those requiring microvascular reconstruction (P = 0.004). The 5-year overall survival of the entire study group was 70.4%. The survival of early and locally advanced stages was 75.1% and 68.4%, respectively. The factors influencing survival were age (>50 years), advanced cT stage, nodal metastasis, overall stage, and presence of orocutaneous fistula. CONCLUSION: The morbidity, mortality, and long-term outcomes of surgically treated oral cancer patients at our center are comparable to those treated in the developed world. Aggressive management of postoperative complications is crucial for early recovery and timely initiation of adjuvant treatment.


How to cite this article:
Nair D, Singhvi H, Mair M, Qayyumi B, Deshmukh A, Pantvaidya G, Nair S, Chaturvedi P, Laskar SG, Prabhash K, DCruz A. Outcomes of surgically treated oral cancer patients at a tertiary cancer center in India.Indian J Cancer 2017;54:616-620


How to cite this URL:
Nair D, Singhvi H, Mair M, Qayyumi B, Deshmukh A, Pantvaidya G, Nair S, Chaturvedi P, Laskar SG, Prabhash K, DCruz A. Outcomes of surgically treated oral cancer patients at a tertiary cancer center in India. Indian J Cancer [serial online] 2017 [cited 2021 Sep 26 ];54:616-620
Available from: https://www.indianjcancer.com/article.asp?issn=0019-509X;year=2017;volume=54;issue=4;spage=616;epage=620;aulast=Nair;type=0