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Figure 3: (a and b) Case of a schwannoma with degenerative atypia (Ancient schwannoma), misdiagnosed as malignant peripheral nerve sheath tumor (H and E, ×200). (c) Case of a low-grade malignant peripheral nerve sheath tumor, misdiagnosed as an inflammatory myofibroblastic tumor (H and E, ×200). Inset: Higher magnification showing hypercellular tumor areas showing nuclear atypia and interspersed mitotic figures (H and E, ×400). (d) Significant tumor cells showing S100 protein positivity, reinforcing nerve sheath differentiation in this case (DAB, ×200)

Figure 3: (a and b) Case of a schwannoma with degenerative atypia (Ancient schwannoma), misdiagnosed as malignant peripheral nerve sheath tumor (H and E, ×200). (c) Case of a low-grade malignant peripheral nerve sheath tumor, misdiagnosed as an inflammatory myofibroblastic tumor (H and E, ×200). Inset: Higher magnification showing hypercellular tumor areas showing nuclear atypia and interspersed mitotic figures (H and E, ×400). (d) Significant tumor cells showing S100 protein positivity, reinforcing nerve sheath differentiation in this case (DAB, ×200)