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Figure 4: NBI guidance for targeted biopsy to increase the yield. (a) WLE: Large bulge with no ulcerated area (b) NBI: Afferent vessels (black arrows) and scaterred brown dots (white arrows) seen in the right ventricle. (c) WLE showing leukoplakia with raised lesion on both vocal cords (d) NBI: Clear areas of scattered brown dots with vascular atypias (Type Vb) seen on the right vocal cord with involvement of anterior commissure. (e) WLE showing a large bulge (f) NBI: Snake like vessels on the medial surface of the bulge. Targeted biopsies from these areas in all three cases revealed invasive SCC

Figure 4: NBI guidance for targeted biopsy to increase the yield. (a) WLE: Large bulge with no ulcerated area (b) NBI: Afferent vessels (black arrows) and scaterred brown dots (white arrows) seen in the right ventricle. (c) WLE showing leukoplakia with raised lesion on both vocal cords (d) NBI: Clear areas of scattered brown dots with vascular atypias (Type Vb) seen on the right vocal cord with involvement of anterior commissure. (e) WLE showing a large bulge (f) NBI: Snake like vessels on the medial surface of the bulge. Targeted biopsies from these areas in all three cases revealed invasive SCC